Received mine yesterday (thanks Art!)
While I normally prefer the traditionally bound books, this spiral bound version will actually be much easier to use on a daily level. (If you actively collect US coins, I would recommend having at least 1 spiral bound version.)
I have not had a chance to read the contents yet, but just from browsing the pages, I agree with others here that the new layout (colored tables, headers, etc.) is excellent- much easier to read. New photos and other info has been added as well. I thought it might be redundant (and to a certain extent it is of course) to get a 2006 as I just bought my first Red Book (2005) earlier in the year, but I am not at all disappointed. It was a positive and pleasant surprise!